Tesamorelin 20mg – Targeted Adipose Research & GHRH Study

Description

What is Tesamorelin & CAS 218949-48-5?

Tesamorelin, identified by the CAS number 218949-48-5, is a synthetic analogue of the human Growth Hormone-Releasing Hormone (GHRH). It is a stabilized peptide consisting of 44 amino acids with an added hexenoyl group, which significantly increases its resistance to enzymatic degradation compared to natural GHRH.

In clinical and laboratory research, Tesamorelin is recognized as one of the most potent secretagogues for stimulating the endogenous release of growth hormone. At 99Purity-Peptide, we provide Tesamorelin 20mg as a high-purity lyophilized powder, specifically engineered for research into lipodystrophy, metabolic optimization, and targeted adipose tissue reduction.

Tesamorelin (CAS 218949-48-5) Mechanism of Action and Research

The mechanism of Tesamorelin involves the direct stimulation of GHRH receptors in the anterior pituitary gland. By mimicking natural GHRH signaling, it triggers the pulsatile release of growth hormone (GH), which subsequently interacts with receptors on various tissues, including adipocytes (fat cells). Unlike other GH secretagogues, Tesamorelin is highly researched for its ability to reduce Visceral Adipose Tissue (VAT)—the deep abdominal fat associated with metabolic syndrome—without negatively impacting glucose levels or subcutaneous fat.

Researchers utilize this peptide to study the intricate relationship between GH levels and lipid distribution. Its structural stability allows for consistent data collection in longitudinal metabolic studies, making it a foundational compound for investigating the reversal of abdominal obesity and the improvement of lipid profiles in biological models.

Trending Research Topics & High-Authority Insights:

• Visceral Adipose Reduction: The impact of GHRH analogues on deep abdominal fat markers.

• GH/IGF-1 Axis Optimization: Studying the long-term metabolic benefits of endogenous GH pulses.

• Tesamorelin and the management of abdominal fat – Project Topaz

Tesamorelin Specifications

Feature	Specification
Product Name	Tesamorelin
Available Strengths	2mg, 5mg, 10mg, 20mg
Physical Appearance	White Lyophilized Powder
Purity	≥ 99% (HPLC/MS Verified)
Molecular Formula	$C_{221}H_{366}N_{72}O_{67}S_{1}$
Molecular Weight	5135.9 g/mol
CAS Number	218949-48-5
Verification	3rd-Party Lab Tested with COA
Storage Instructions	Store at -20°C (Long-term); 2-8°C after reconstitution

Tesamorelin Key Features & Benefits

• Targeted Adipose Research: The gold standard for investigating the reduction of visceral fat in metabolic models.

• Endogenous GH Stimulation: Research-grade secretagogue that promotes natural growth hormone secretion.

• Elite Purity Standards: Synthesized at 99%+ purity to ensure experimental reliability and eliminate contaminants.

• Vacuum-Sealed Lyophilization: Professionally freeze-dried to maintain molecular integrity during global shipping and long-term storage.

• HPLC/MS Verified: Every batch is independently verified to confirm the precise 44-amino acid sequence and potency.

Tesamorelin FAQ

Why is Tesamorelin 20mg preferred for visceral fat studies?

Tesamorelin specifically targets visceral fat (VAT) while sparing subcutaneous fat. In research, this allows for the study of high-risk abdominal fat reduction without affecting the patient’s overall fat distribution or insulin sensitivity.

How does Tesamorelin differ from CJC-1295?

While both are GHRH analogues, Tesamorelin was specifically developed for its lipolytic (fat-burning) effects. It is often studied for its targeted impact on liver fat and abdominal adipose tissue, whereas CJC-1295 is used for more generalized GH research.

What is the best way to store Tesamorelin 20mg vials?

The lyophilized powder is highly stable and should be stored at -20°C. Once the peptide is reconstituted with bacteriostatic water, it should be kept in a refrigerator (2-8°C) and utilized within 14-21 days for maximum research efficacy.

Does 99Purity-Peptide provide third-party testing?

Absolutely. Every order of Tesamorelin comes with a Certificate of Analysis (COA) confirming that the product meets the strict 99%+ purity requirements for professional laboratory use.

Why Buy Tesamorelin online from 99Purity-Peptide?

• Scientific Precision & Consistency: We specialize in providing high-concentration 20mg vials with exact purity levels, ensuring your research data is reproducible and accurate.

• Discreet & Secure Logistics: We prioritize your research privacy. All products are shipped in neutral, secure packaging with tracked, expedited delivery to the USA, UK, and Europe.

• Entrepreneurial Reliability: As a boutique biotech supplier, we offer 1-2 business day dispatch and maintain rigorous stock standards for high-demand peptides.

• Verified Quality Guarantee: Every purchase is backed by HPLC and Mass Spectrometry data, ensuring you receive the highest quality materials for your metabolic research projects.

Payment Support & Logistics

• Secure Payment Options: We support multiple secure gateways, including Credit Cards, Cryptocurrency (USDT, USDC), PayPal, and Bank Transfers.

• Global Shipping: Fast, tracked delivery available to the United States, United Kingdom, and Europe.

• Processing Time: All orders are professionally handled and dispatched within 1-2 business days after payment confirmation.

Regulatory Disclaimer

99Purity-Peptide is a chemical supplier. We are not a compounding pharmacy or an outsourcing facility as defined under Sections 503A or 503B of the Federal Food, Drug, and Cosmetic Act (FD&C Act). All products are strictly for research, laboratory, or analytical use only and are NOT for human consumption.

References & Academic Links

• Falutz, J., et al. (2007). “Effects of Tesamorelin, a Growth Hormone-Releasing Hormone Analogue, in HIV-Infected Patients with Abdominal Fat Accumulation.” New England Journal of Medicine.

• Spooner, R. K., et al. (2012). “Tesamorelin: a growth hormone-releasing hormone analogue for the treatment of HIV-associated lipodystrophy.” Drug Design, Development and Therapy.