SS-31 Peptide (Elamipretide) 50mg – Mitochondrial Cardiolipin Stabilization Research

Description

What is SS-31 (Elamipretide) & CAS 733039-20-8?

To achieve reproducible data in the field of metabolic research, scientists increasingly rely on mitochondria-targeted compounds. SS-31, also known as Elamipretide (CAS 733039-20-8), is a small, water-soluble tetrapeptide (D-Arg-2′,6′-dimethyl-Tyr-Lys-Phe-NH2) that possesses the unique ability to penetrate the cell membrane and localize specifically within the inner mitochondrial membrane (IMM). It is engineered for research into cellular energy optimization and the mitigation of oxidative damage. Unlike general antioxidants, SS-31 targets the source of reactive oxygen species (ROS) production, making it a foundational subject for investigators exploring multi-organ recovery and the biological mechanisms of aging.

Synthesized to meet elite laboratory standards, our SS-31 50mg (and 10mg) vials are provided as a sterile, vacuum-sealed lyophilized powder. This high-purity preparation is essential for maintaining the peptide’s structural fidelity, as the elamipretide sequence is sensitive to environmental moisture and thermal fluctuations. At 99Purity-Peptide, we utilize advanced freeze-drying technology to ensure that the mitochondrial-targeting capabilities of the peptide remain intact throughout global transit.

SS-31 (Elamipretide) Mechanism of Action and Research

Targeting the specific markers of mitochondrial dysfunction, SS-31 functions by binding selectively to cardiolipin, a unique phospholipid located in the inner mitochondrial membrane. In a laboratory environment, researchers have observed that this binding stabilizes the cristae structure and promotes the efficient transfer of electrons through the respiratory chain. By leveraging these properties, SS-31 research focuses on its ability to increase ATP production while simultaneously reducing the electron “leakage” that leads to oxidative stress and cellular apoptosis.

Advancing the understanding of organ-specific repair, contemporary studies utilize SS-31 to evaluate its efficacy in cardiac, renal, and neurological research models. Emerging data from high-fidelity laboratory trials suggests that by optimizing mitochondrial bioenergetics, SS-31 may help restore functional capacity in tissues high in energy demand. Its role in protecting the mitochondrial matrix makes it a primary subject for research into ischemia-reperfusion injury and systemic metabolic health optimization.

Trending Research Topics & High-Authority Insights:

• Mitochondrial Cardiolipin Stabilization: Investigating the recovery of the respiratory chain.

• Peptide-Mediated ATP Optimization: The future of cellular energy research.

• SS-31 and the restoration of mitochondrial function in aging models – PubMed

SS-31 (Elamipretide) Specifications

Feature	Specification
Product Name	SS-31 (Elamipretide)
Available Strengths	10mg, 50mg
Physical Appearance	White Lyophilized Powder
Purity	≥ 99% (HPLC/MS Verified)
Verification Method	3rd-Party Lab Tested with COA
Storage Instructions	Store at -20°C (Long-term); 2-8°C after reconstitution
Molecular Formula	$C_{32}H_{49}N_{9}O_{5}$
Molecular Weight	639.80 g/mol
CAS Number	733039-20-8

SS-31 Key Features & Benefits

• Mitochondria-Targeted Peptide: Specifically researched for its unique ability to bind to cardiolipin and stabilize mitochondrial membranes.

• Energy Metabolism Subject: Optimized for studies involving ATP production efficiency and oxidative stress reduction.

• High-Purity Laboratory Grade: Synthesized at 99%+ purity to ensure clean experimental data without the interference of chemical byproducts.

• Vacuum-Sealed Stability: Delivered as a sterile freeze-dried powder to maximize shelf life and resist proteolytic degradation.

• Independently Verified Identity: Each batch is confirmed via HPLC and Mass Spectrometry for absolute amino acid sequence fidelity.

SS-31 (Elamipretide) FAQ

How does SS-31 differ from standard antioxidants?

General antioxidants neutralize free radicals after they have already been formed. In research models, SS-31 is observed to prevent the excessive formation of free radicals at the source by optimizing the mitochondrial electron transport chain. This “upstream” intervention makes it a highly valued subject for studying cellular recovery.

Why is the 50mg high-dose vial preferred for metabolic studies?

Mitochondrial research protocols often involve complex dosing schedules to observe changes in systemic bioenergetics. The 50mg strength provides researchers with sufficient material for extensive longitudinal studies, ensuring that batch-to-batch variability is eliminated throughout the duration of the experiment.

What is the most effective way to reconstitute SS-31 50mg?

To achieve reproducible data, SS-31 should be reconstituted with sterile bacteriostatic water. The liquid should be added slowly along the side of the vial. A gentle swirling motion is sufficient; avoid vigorous shaking to protect the tetrapeptide structure from mechanical stress.

Can SS-31 be researched alongside other repair peptides?

Yes. Many laboratory protocols explore the synergy between SS-31 (mitochondrial focus) and tissue-specific peptides like BPC-157 or MOTS-c to observe a multi-faceted approach to organ repair and systemic energy optimization.

Why Buy SS-31 online from 99Purity-Peptide?

• Elite Synthesis Standards: We prioritize the chemical precision required for high-stakes mitochondrial research, ensuring every vial of SS-31 meets our 99%+ purity benchmark.

• Reliable Batch-to-Batch Quality: Our manufacturing protocols ensure that the bio-activity and purity of our Elamipretide remain identical in every vial, supporting credible long-term results.

• Discreet & Tracked Logistics: Your research privacy is a priority. All orders feature unbranded, secure packaging with expedited tracked shipping to the USA, UK, and Europe.

• Researcher Protections: From 3rd-party lab verification (COA) to 1-2 business day dispatch, we provide the professional reliability that modern biotechnology researchers demand.

Payment Support & Logistics

• Secure Payment Options: We support multiple secure gateways, including Credit Cards, Cryptocurrency (USDT, USDC), PayPal, and Bank Transfers.

• Global Shipping: Fast, tracked delivery available to the United States, United Kingdom, and Europe.

• Processing Time: All orders are professionally handled and dispatched within 1-2 business days after payment confirmation.

Regulatory Disclaimer

99Purity-Peptide is a chemical supplier. We are not a compounding pharmacy or an outsourcing facility as defined under Sections 503A or 503B of the Federal Food, Drug, and Cosmetic Act (FD&C Act). All products are strictly for research, laboratory, or analytical use only and are NOT for human consumption.

References & Academic Links

• Szeto, H. H. (2014). “First-in-class cardiolipin-protective compound (SS-31) for mitochondrial medicine.” British Journal of Pharmacology.

• Brown, D. A., et al. (2011). “The mitochondria-targeted peptide SS-31 improves myocardial function.” ScienceDirect – Journal of Molecular and Cellular Cardiology.

• Birk, A. V., et al. (2013). “The essential role of cardiolipin in mitochondrial structure and its protection by SS-31.” PubMed – Archives of Biochemistry and Biophysics.