Aicar 50mg – High-Purity Nucleoside Signaling Standard for Metabolic Research

Description

What is Aicar & CAS 2627-69-2?

Delivering Aicar (Acadesine) in a pristine, lyophilized state allows for maximum experimental flexibility and ensures that its chemical structure remains stable for long-term observation. Scientifically known as 5-Aminoimidazole-4-carboxamide ribonucleotide, Aicar is a cell-permeable nucleoside that plays a pivotal role in cellular energy regulation. It is a synthetic analog of adenosine monophosphate (AMP) that has gained significant attention in biotechnology for its ability to influence metabolic signaling without altering cellular ATP levels.

Our specialized synthesis process at 99Purity-Peptide guarantees a consistent 99%+ purity level for our Aicar 50mg and 100mg vials. This high-fidelity material is essential for researchers investigating the complex pathways of nutrient sensing and energy balance, providing a reliable subject that is free from the contaminants or degradants that can compromise sensitive biological data.

Aicar (CAS 2627-69-2) Mechanism of Action and Research

The primary research value of Aicar lies in its role as a master regulator of the AMP-activated protein kinase (AMPK) pathway. By activating AMPK, Aicar mimics a state of low cellular energy, which in turn stimulates glucose uptake and fatty acid oxidation. In laboratory models, this mechanism is extensively studied to observe its impact on metabolic flexibility and its potential to enhance mitochondrial biogenesis, effectively “tricking” the cells into increasing energy expenditure as if under conditions of physical exertion.

Beyond lipid metabolism, Aicar is at the forefront of research into cardiovascular health and skeletal muscle adaptation. Scientists utilize this compound to explore its effects on reducing inflammation and improving blood flow in ischemic models. Its ability to modulate cellular metabolism at a fundamental level makes it a foundational tool for contemporary studies into metabolic disorders and performance-related aging research.

Trending Research Topics & High-Authority Insights:

• AMPK Signaling and Glucose Homeostasis: Investigating non-insulin pathways for cellular energy management.

• Aicar and Mitochondrial Biogenesis: Studies on exercise-mimetic peptides in muscle tissue.

• AMPK Activation and Metabolic Health – ScienceDirect

Aicar Specifications

Aicar Key Features & Benefits

• Pioneering Metabolic Research Subject: The gold standard for investigating AMPK-mediated energy regulation.

• Exercise Mimetic Properties: Targeted for studies focusing on fatty acid oxidation and glucose uptake.

• Pharmaceutical Grade Synthesis: Produced at 99%+ purity to eliminate experimental noise and ensure reproducible results.

• Sterile Freeze-Dried Stability: Vacuum-sealed to maintain molecular integrity during global transit and long-term storage.

• Verified Purity & Identity: Every batch is confirmed via HPLC and Mass Spectrometry to guarantee chemical precision.

Aicar Research FAQ

Why is Aicar commonly referred to as an “exercise mimetic”?

In research environments, Aicar activates the same metabolic pathways (specifically AMPK) that are triggered during intense cardiovascular exercise. This allows scientists to study the effects of increased energy expenditure and fat mobilization without the need for physical stimulation.

What is the advantage of the 50mg lyophilized vial?

The 50mg concentration is optimized for precise laboratory scaling. By providing it as a lyophilized powder, we ensure the molecule remains “locked” in its stable form, preventing the degradation that often occurs with pre-mixed liquid solutions.

How should Aicar be stored once it arrives at the lab?

For long-term storage, the unopened vial should be kept in a freezer at -20°C. Once reconstituted with bacteriostatic water or sterile saline, the solution must be refrigerated (2-8°C) and ideally utilized within 14 days for peak research accuracy.

Is the CAS 2627-69-2 identity verified for every batch?

Yes. 99Purity-Peptide provides a 3rd-party Certificate of Analysis (COA) for each shipment, confirming the molecular weight and purity via HPLC/MS to ensure your data is backed by verified chemical standards.

Why Buy Aicar online from 99Purity-Peptide?

• Unmatched Scientific Integrity: We understand that your research is only as good as your materials. Our Aicar is synthesized to meet the most rigorous analytical benchmarks.

• Discreet & Tracked Logistics: We prioritize the safe and private delivery of your supplies. All orders feature unbranded, secure packaging with expedited shipping to the USA, UK, and Europe.

• Reliable Batch Consistency: Our production protocols ensure that the chemical profile of our Aicar remains identical from one order to the next, supporting long-term, credible research data.

• Total Transparency: From 3rd-party lab verification to a secure purchase environment, we provide the professional reliability that serious metabolic researchers demand.

Payment Support & Logistics

• Secure Payment Options: We support multiple secure gateways, including Credit Cards, Cryptocurrency (USDT, USDC), PayPal, and Bank Transfers.

• Global Shipping: Fast, tracked delivery available to the United States, United Kingdom, and Europe.

• Processing Time: All orders are professionally handled and dispatched within 1-2 business days after payment confirmation.

Regulatory Disclaimer

99Purity-Peptide is a chemical supplier. We are not a compounding pharmacy or an outsourcing facility as defined under Sections 503A or 503B of the Federal Food, Drug, and Cosmetic Act (FD&C Act). All products are strictly for research, laboratory, or analytical use only and are NOT for human consumption.

References & Academic Links

• Narkar, V. A., et al. (2008). “AMPK and PPARδ Agonists Are Exercise Mimetics.” Cell.

• Corton, J. M., et al. (1995). “5-Aminoimidazole-4-carboxamide ribonucleoside: A specific method for activating AMP-activated protein kinase in intact cells?” European Journal of Biochemistry.

• Long, Y. C., & Zierath, J. R. (2006). “AMP-activated protein kinase: Signaling pathways and cellular functions.” Journal of Clinical Investigation.

• Suwa, M., et al. (2003). “AICAR increases mitochondrial enzymes and type IIa/x fiber content in rat muscle.” Journal of Applied Physiology.