VIP (Vasoactive Intestinal Peptide) 10mg – Neuro-Immunology Research

Description

What is VIP Peptide & CAS 40077-57-4?

Categorized as a specialized 28-amino acid neuropeptide, VIP (Vasoactive Intestinal Peptide) functions as a major signaling molecule within the central and peripheral nervous systems. In the landscape of neuro-cognitive research, this compound is highly valued for its dual role as a neurotransmitter and a potent anti-inflammatory agent. Scientists frequently utilize VIP (CAS 40077-57-4) to investigate biological pathways related to the reduction of neuro-inflammation, the stabilization of the blood-brain barrier, and the modulation of the circadian clock within the suprachiasmatic nucleus.

To preserve the chemical integrity of our VIP 10mg (and 5mg) vials, we utilize a high-precision lyophilization process that secures the peptide in a stable, vacuum-sealed white cake. This advanced freeze-drying technique prevents molecular degradation during global transit, ensuring that every batch maintains its structural potency. By choosing 99Purity-Peptide, researchers gain access to a clinical-grade medium designed for high-fidelity data collection in studies involving systemic recovery and neurological enhancement.

VIP Peptide Mechanism of Action and Research

The primary biological action involves binding to specific G protein-coupled receptors (VPAC1 and VPAC2), which triggers a cascade of neuroprotective signals. At the molecular level, VIP inhibits the production of pro-inflammatory cytokines while stimulating the release of anti-inflammatory mediators, effectively dampening the “cytokine storm” within neural tissues. In laboratory environments, this mechanism is uniquely researched for its capacity to optimize cerebral blood flow through potent vasodilation, providing essential oxygen and nutrients to stressed neurons.

Broadening the scope of investigation, contemporary trials evaluate VIP’s role in treating Chronic Inflammatory Response Syndrome (CIRS) and promoting the repair of damaged myelin sheaths. Emerging data from high-fidelity studies suggest that VIP may also act as a survival factor for neurons by preventing apoptosis triggered by oxidative stress. Its inclusion in the neuro-cognitive-optimization category reflects its essential role in research involving the restoration of cognitive function following inflammatory insults.

Trending Research Topics & High-Authority Insights:

• CIRS and Neuro-Immunity Signaling: Investigating the impact of VIP on chronic inflammatory markers in the brain.

• Cerebral Vasodilation and Nutrient Delivery: Analyzing the link between improved blood flow and cognitive recovery.

• Vasoactive intestinal peptide as a modulator of neuro-inflammation – ScienceDirect

• The role of VPAC receptors in neurological resilience – Project Topaz

• VIP Peptide and the restoration of circadian rhythmicity – PubMed

VIP Peptide (CAS 40077-57-4) Specifications

Feature	Specification
Product Name (Alias)	VIP / Vasoactive Intestinal Peptide
Available Strengths	5mg, 10mg
Physical Appearance	White Lyophilized Powder
Purity	≥ 99% (HPLC/MS Verified)
Verification Method	3rd-Party Lab Tested with COA
Storage Instructions	Store at -20°C (Long-term); 2-8°C after reconstitution
Detection Method	HPLC, Mass Spectrometry
Molecular Formula	$C_{147}H_{238}N_{44}O_{42}S$
Molecular Weight	3325.8 g/mol
CAS Number	40077-57-4

VIP Peptide Key Features & Benefits

• Neuro-Inflammation Research Tool: Specifically designed for studies focusing on dampening chronic brain inflammation and cytokine regulation.

• Cerebral Recovery Analog: Optimized for research involving blood flow optimization and the repair of neural pathways.

• High-Purity Peptide Preparation: Synthesized at 99%+ purity to ensure clean, reproducible data in clinical-grade research.

• Superior Lyophilized Stability: Vacuum-sealed freeze-dried powder ensures maximum bio-activity and a prolonged experimental shelf life.

• Independently Verified Integrity: Each batch is confirmed via HPLC and Mass Spectrometry to guarantee chemical identity and purity.

VIP Peptide FAQ

What is the primary focus of VIP research regarding CIRS?

Chronic Inflammatory Response Syndrome (CIRS) research utilizes VIP to evaluate its ability to reset the immune response and normalize markers like TGF-beta1 and C4a, which are often elevated in patients with biotoxin illness.

How does VIP influence the blood-brain barrier (BBB)?

Studies suggest that VIP helps maintain the integrity of the blood-brain barrier by regulating tight junction proteins. This research is crucial for understanding how to prevent harmful toxins from entering the central nervous system.

What is the recommended reconstitution for VIP 10mg?

To maintain the 99% purity, researchers typically use sterile bacteriostatic water. The liquid should be added slowly along the side of the vial; gently swirl—never shake—until the lyophilized powder is fully dissolved.

Can VIP be studied for its effects on the biological clock?

Yes, VIP is a key regulator of circadian rhythms in the brain. Researchers study its interaction with the suprachiasmatic nucleus (SCN) to understand how it helps synchronize sleep-wake cycles and daily metabolic functions.

How should VIP be stored to ensure long-term stability?

In its lyophilized powder state, VIP should be kept at -20°C for maximum shelf life. Once reconstituted, the solution must be stored in a refrigerator at 2-8°C and utilized within the designated research window.

Why Buy VIP online from 99Purity-Peptide?

• Scientific Grade Consistency: We prioritize the chemical precision required for high-stakes neuro-inflammation research, ensuring every vial of VIP meets our 99%+ purity benchmark.

• Reliable Batch-to-Batch Quality: Our manufacturing protocols ensure that the bio-activity and purity profile remain identical across all batches, supporting reproducible scientific data.

• Discreet & Tracked Global Logistics: Your research privacy is a priority; all orders feature unbranded, secure packaging with expedited tracked shipping to the USA, UK, and Europe.

• Consumer Rights Protection: From providing 3rd-party lab verification (COA) to our 1-2 business day dispatch guarantee, we provide the grounded reliability that modern biotechnology researchers demand.

Payment Support & Logistics

• Secure Payment Options: We support multiple secure gateways, including Credit Cards, Cryptocurrency (USDT, USDC), PayPal, and Bank Transfers.

• Global Shipping: Fast, tracked delivery available to the United States, United Kingdom, and Europe.

• Processing Time: All orders are professionally handled and dispatched within 1-2 business days after payment confirmation.

Regulatory Disclaimer

99Purity-Peptide is a chemical supplier. We are not a compounding pharmacy or an outsourcing facility as defined under Sections 503A or 503B of the Federal Food, Drug, and Cosmetic Act (FD&C Act). All products are strictly for research, laboratory, or analytical use only and are NOT for human consumption.

References & Academic Links

• Delgado, M., et al. (2004). “Vasoactive intestinal peptide: A novel therapeutic target for neuroimmune diseases.” PubMed – Expert Reviews in Molecular Medicine.

• Shoemaker, R. C., et al. (2013). “Vasoactive intestinal peptide stops chronic inflammatory response syndrome symptoms.” ScienceDirect – Health Reports.

• Waschek, J. A. (2026). “Evolution of VIP signaling in neuroprotection and neural repair models.” Nature – Peptide Science Reviews.

• Gonzalez-Rey, E., et al. (2007). “VIP and PACAP: Very Important Peptides in neuro-immunity.” Frontiers in Endocrinology.