Matrixyl 10mg – Anti-Aging & Dermal Collagen Research
A powerful palmitoyl-pentapeptide. Optimized for research into collagen synthesis, skin matrix repair, and the reduction of fine lines and deep-seated wrinkles.
Description
What is Matrixyl & CAS 214047-00-4?
Advancing the study of dermal structural integrity requires highly stable signaling molecules. Matrixyl, scientifically known as Palmitoyl Pentapeptide-4 (CAS 214047-00-4), is a specialized lipopeptide designed to facilitate deep-tissue research. It consists of a five-amino acid chain linked to a palmitic acid fatty acid chain. This unique biochemical architecture is engineered to enhance the molecule’s lipophilicity, allowing researchers to observe its interaction with the lipid-rich barriers of dermal cell membranes.
At 99Purity-Peptide, we provide Matrixyl in a pristine, lyophilized (freeze-dried) state. This professional-grade preparation ensures that the pentapeptide sequence remains stable and bioactive, free from the premature degradation often found in liquid-based cosmetic raw materials. Each 10mg vial is vacuum-sealed to provide a consistent and high-fidelity subject for studies on extracellular matrix (ECM) restoration.
Matrixyl (CAS 214047-00-4) Mechanism of Action and Research
The research value of Matrixyl lies in its role as a “matrikine”—a messenger peptide capable of regulating cell activity. In laboratory models, Matrixyl is observed to trigger a feedback loop that stimulates the production of Type I, III, and IV collagen, as well as fibronectin and glycosaminoglycans. By mimicking the natural fragments of broken-down collagen, the peptide “signals” fibroblasts to initiate the synthesis of new structural proteins, making it a cornerstone for studies investigating the biological reversal of photo-aging.
Scientific investigations utilize Matrixyl to explore the strengthening of the dermal-epidermal junction (DEJ). Researchers study its potential to improve the density of skin tissue and its efficacy in repairing environmental damage at a cellular level. Its non-irritating nature and targeted mechanism make it a premier candidate for long-term studies in regenerative dermatology and anti-aging biotechnology.
Trending Research Topics & High-Authority Insights:
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Fibroblast Rejuvenation Signaling: Investigating endogenous collagen synthesis pathways.
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Lipopeptide Dermal Permeability: The role of fatty acid chains in peptide delivery research.
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Matrikines and the Regulation of Dermal Extracellular Matrix – ScienceDirect
Matrixyl Specifications
| Feature | Specification |
| Product Name | Matrixyl (Palmitoyl Pentapeptide-4) |
| Available Strengths | 10mg |
| Physical Appearance | White Lyophilized Powder |
| Purity | ≥ 99% (HPLC/MS Verified) |
| Molecular Formula | $C_{39}H_{75}N_{7}O_{10}$ |
| Molecular Weight | 802.05 g/mol |
| CAS Number | 214047-00-4 |
| Verification Method | 3rd-Party Lab Tested with COA |
| Storage Instructions | Store at -20°C (Long-term); 2-8°C after reconstitution |
Matrixyl Key Features & Benefits
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Advanced Collagen Synthesis Subject: Specifically researched for its ability to stimulate Type I and Type IV collagen production.
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Skin Matrix Repair Focus: Ideal for studies exploring the restoration of the extracellular matrix and dermal density.
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Pharmaceutical Grade Synthesis: Produced at 99%+ purity to eliminate variables and ensure reproducible experimental results.
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Sterile Freeze-Dried Stability: Vacuum-sealed to resist oxidation and environmental degradation during transit.
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Independently Verified Identity: Each vial is confirmed via HPLC and Mass Spectrometry for absolute peptide sequence accuracy.
Matrixyl Research FAQ
How does Matrixyl compare to traditional peptides in collagen research?
Unlike many linear peptides that struggle to bypass cellular barriers, Matrixyl features a palmitoyl chain that enhances lipophilicity. In a laboratory setting, this allows for more effective study of fibroblast activation and matrix protein signaling compared to non-modified pentapeptides.
Why is the 10mg lyophilized format preferred over liquid serums?
For scientific research, liquid products often contain preservatives and stabilizers that can interfere with experimental data. Our 10mg lyophilized powder is the pure peptide in its most stable form, allowing researchers to control the concentration precisely.
What is the recommended reconstitution protocol for Matrixyl 10mg?
Researchers typically use sterile saline or bacteriostatic water. The liquid should be introduced slowly down the side of the vial. Due to the palmitic acid chain, gentle swirling is recommended to ensure complete dissolution without denaturing the peptide chain.
Can Matrixyl be studied for its effects on environmental skin damage?
Yes. Matrixyl is frequently used in long-term studies focusing on the repair of the skin matrix after exposure to UV radiation or oxidative stress, helping scientists observe how matrikines reset cellular health.
Why Buy Matrixyl online from 99Purity-Peptide?
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Scientific Grade Consistency: We prioritize the chemical precision required for high-stakes research, ensuring every vial of Matrixyl meets our rigorous 99%+ purity benchmark.
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Discreet & Tracked Logistics: Your research privacy is essential. All orders are sent in neutral, secure packaging with tracked delivery to the USA, UK, and Europe.
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Reliable Batch Purity: Our manufacturing protocols ensure that the chemical profile of our Matrixyl remains identical batch-after-batch, supporting credible and valid long-term data.
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Total Researcher Rights Protection: From 3rd-party lab verification (COA) to 1-2 business day dispatch, we provide the professional reliability that modern researchers demand.
Payment Support & Logistics
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Secure Payment Options: We support multiple secure gateways, including Credit Cards, Cryptocurrency (USDT, USDC), PayPal, and Bank Transfers.
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Global Shipping: Fast, tracked delivery available to the United States, United Kingdom, and Europe.
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Processing Time: All orders are professionally handled and dispatched within 1-2 business days after payment confirmation.
Regulatory Disclaimer
99Purity-Peptide is a chemical supplier. We are not a compounding pharmacy or an outsourcing facility as defined under Sections 503A or 503B of the Federal Food, Drug, and Cosmetic Act (FD&C Act). All products are strictly for research, laboratory, or analytical use only and are NOT for human consumption.
References & Academic Links
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Robinson, L. R., et al. (2005). “Topical palmitoyl pentapeptide-4 provides anti-aging benefits to facial skin.” International Journal of Cosmetic Science.
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Sederma Research Lab. (2002). “Synthesis of Collagen and Fibronectin by Human Fibroblasts Stimulated with Pal-KTTKS.” In Vitro Dermal Study.
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Zhang, L., & Falla, T. J. (2009). “Cosmeceutical peptides: mechanisms of action and research applications.” Clinics in Dermatology.








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