Snap-8 100mg – Research on Neuromuscular Signaling & Dermal Smoothness
Price range: £29.89 through £291.79
An octapeptide analog of Argireline. Specialized for research into muscle contraction modulation, reduction of expression lines, and advanced anti-wrinkle dermal studies.
Description
What is Snap-8 & CAS 607339-12-8?
Precision in topical neurotransmitter modulation begins with high-purity signaling molecules. Snap-8 (Acetyl Octapeptide-3) is an elongated, more potent analog of the well-known hexapeptide Argireline. Registered under CAS 607339-12-8, this octapeptide is engineered to mimic the N-terminal end of the SNAP-25 protein. Its primary role in a laboratory setting is to compete for a position in the SNARE (Soluble N-ethylmaleimide-sensitive factor Attachment Protein Receptor) complex, which is essential for cellular exocytosis and neurotransmitter release.
At 99Purity-Peptide, we provide Snap-8 in a stabilized, lyophilized (freeze-dried) state to ensure the peptide sequence remains bioactive and resistant to thermal degradation. Available in 10mg and 100mg vials, our Snap-8 is synthesized for researchers investigating the non-invasive reduction of expression lines and the biochemical stabilization of dermal matrices.
Snap-8 (CAS 607339-12-8) Mechanism of Action and Research
The research value of Snap-8 lies in its “botulinum-like” mechanism, executed without the toxicity associated with bacterial toxins. In laboratory models, Snap-8 destabilizes the SNARE complex by mimicking one of its components. When the SNARE complex is slightly destabilized, the release of acetylcholine—the neurotransmitter responsible for muscle contraction—is significantly modulated. By reducing the intensity of these micro-contractions in vitro, researchers can observe a measurable decrease in the formation of deep-seated expression lines and repetitive motion wrinkles.
Scientific investigations currently utilize Snap-8 to explore the synergy between neurotransmitter modulation and dermal hydration. Beyond its impact on muscle-driven lines, researchers study its potential to improve the overall texture of the skin by reducing mechanical stress on fibroblasts. Its high degree of safety and targeted inhibitory mechanism make it a foundational subject for advanced anti-aging biotechnology and regenerative dermatology studies.
Trending Research Topics & High-Authority Insights:
SNARE Complex Destabilization: Investigating non-toxic neurotransmitter inhibition.
Topical Neuro-Modulators in Dermatology: Studies on the efficacy of octapeptides vs. hexapeptides.
Acetyl Octapeptide-3 and the mechanism of neurotransmitter release – Project Topaz
Snap-8 Specifications
| Feature | Specification |
| Product Name | Snap-8 (Acetyl Octapeptide-3) |
| Available Strengths | 10mg, 100mg |
| Physical Appearance | White Lyophilized Powder |
| Purity | ≥ 99% (HPLC/MS Verified) |
| Molecular Formula | $C_{41}H_{70}N_{16}O_{16}S_{1}$ |
| Molecular Weight | 1075.16 g/mol |
| CAS Number | 607339-12-8 |
| Verification Method | 3rd-Party Lab Tested with COA |
| Storage Instructions | Store at -20°C (Long-term); 2-8°C after reconstitution |
Snap-8 Key Features & Benefits
Advanced Muscle Modulation Subject: Optimized for research into the reduction of expression lines and mechanical dermal stress.
SNARE Complex Antagonist: A specialized tool for studying the inhibition of neuronal exocytosis in laboratory models.
Pharmaceutical Grade Synthesis: Produced at 99%+ purity to eliminate experimental noise and ensure consistent, credible data.
Sterile Freeze-Dried Stability: Vacuum-sealed to maintain molecular integrity during global transit and long-term storage.
Independently Verified Identity: Each vial is confirmed via HPLC and Mass Spectrometry for absolute amino acid sequence accuracy.
Snap-8 Research FAQ
How does Snap-8 compare to Argireline in a research setting?
Snap-8 is an octapeptide (8 amino acids), whereas Argireline is a hexapeptide (6 amino acids). In comparative studies, the longer chain of Snap-8 often demonstrates a more robust ability to destabilize the SNARE complex, leading to more efficient modulation of neurotransmitter release in laboratory models.
Why is the 100mg vial preferred for large-scale dermal studies?
The 100mg configuration allows for the creation of high-concentration stock solutions, which are necessary for longitudinal studies and multi-subject laboratory protocols, ensuring batch consistency across the entire research duration.
What is the recommended storage and handling for Snap-8 100mg?
The lyophilized powder should be stored at -20°C for long-term stability. Once reconstituted with sterile water or bacteriostatic saline, the solution must be refrigerated (2-8°C). Researchers should avoid vigorous shaking to prevent the denaturing of the octapeptide chain.
Can Snap-8 be studied alongside other peptides like Matrixyl?
Yes. Many researchers study the synergistic effects of Snap-8 (which targets muscle-driven lines) with “matrikines” like Matrixyl (which target collagen synthesis) to observe comprehensive dermal remodeling.
Why Buy Snap-8 online from 99Purity-Peptide?
Scientific Grade Consistency: We prioritize chemical precision, ensuring every vial of Snap-8 meets the 99%+ purity requirement essential for high-fidelity research.
Discreet & Tracked Logistics: Your research privacy is a priority. All orders feature unbranded, secure packaging with expedited tracked shipping to the USA, UK, and Europe.
Reliable Batch Purity: Our manufacturing protocols ensure that the chemical profile of our Snap-8 remains identical batch-after-batch, supporting reproducible data.
Total Researcher Protection: From 3rd-party lab verification (COA) to secure payment options, we provide the professional reliability that modern biotechnology researchers demand.
Payment Support & Logistics
Secure Payment Options: We support multiple secure gateways, including Credit Cards, Cryptocurrency (USDT, USDC), PayPal, and Bank Transfers.
Global Shipping: Fast, tracked delivery available to the United States, United Kingdom, and Europe.
Processing Time: All orders are professionally handled and dispatched within 1-2 business days after payment confirmation.
Regulatory Disclaimer
99Purity-Peptide is a chemical supplier. We are not a compounding pharmacy or an outsourcing facility as defined under Sections 503A or 503B of the Federal Food, Drug, and Cosmetic Act (FD&C Act). All products are strictly for research, laboratory, or analytical use only and are NOT for human consumption.
References & Academic Links
Blanes-Mira, C., et al. (2002). “A synthetic hexapeptide (Argireline) with antiwrinkle activity.” International Journal of Cosmetic Science.
Lupo, M. P., & Cole, A. L. (2007). “Cosmeceutical Peptides.” Dermatologic Therapy.
Schagen, S. K. (2017). “Topical Peptide Treatments with Effective Anti-Aging Results.” Cosmetics.
Grosenbach, D. W., et al. (2006). “Cleavage of SNAP-25 by botulinum neurotoxin type A.” Journal of Biological Chemistry.
Pickart, L. (2008). “The human tri-peptide GHK and its copper complex as a treatment for the complications of aging.” Journal of Aging Research.
Additional information
| Weight | 0.5 kg |
|---|---|
| Dimensions | 25 × 20 × 20 cm |
| Strength | 10mg*10Vials, 100mg*10Vials |








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