Melanotan I (MT-1) 10mg – Skin Pigmentation Research

Description

What is Melanotan I (MT-1) & CAS 75921-69-6?

Delivering Melanotan I (MT-1) in a pristine, lyophilized state allows for maximum experimental flexibility and long-term storage stability. Also known as Afamelanotide, MT-1 is a synthetic peptide analog of the naturally occurring melanocyte-stimulating hormone ($\alpha$-MSH). It consists of a linear 13-amino acid sequence that has been modified to enhance its biological potency and resistance to enzymatic degradation compared to its natural counterpart.

Our specialized synthesis process at 99Purity-Peptide guarantees a consistent 99%+ purity level for our Melanotan I 10mg vials. By providing this compound in a vacuum-sealed, freeze-dried format, we ensure that the molecular integrity of the peptide is preserved, offering researchers a stable and research-ready medium for exploring the complex pathways of melanin production and cellular photoprotection.

Melanotan I (MT-1) Mechanism of Action and Research

The research significance of Melanotan I (MT-1) lies in its role as a selective agonist of the Melanocortin 1 Receptor (MC1R) located on the surface of melanocytes. In laboratory models, the activation of MC1R triggers a signaling cascade that stimulates eumelanogenesis—the production of eumelanin, the dark pigment responsible for skin and hair coloration. Unlike other non-selective analogs, MT-1 is primarily studied for its ability to induce pigmentation without significantly affecting other melanocortin receptors associated with appetite or sexual function.

Current scientific investigations focus on the “photoprotective” properties of MT-1. Researchers utilize this peptide to observe how increased melanin density acts as a biological shield against UV-induced DNA damage and oxidative stress. This makes Melanotan I a foundational subject for studies involving erythropoietic protoporphyria (EPP), polymorphic light eruption, and general dermal resilience against solar radiation.

Trending Research Topics & High-Authority Insights:

• MC1R Activation and DNA Repair: Investigating the protective role of melanin in dermal cell kernels.

• Afamelanotide and Phototoxicity: Studies on systemic photoprotection in UV-sensitive models.

• Melanocortin Receptor Signaling and Skin Pigmentation – PubMed

Melanotan I (MT-1) Specifications

Feature	Specification
Product Name	Melanotan I (Afamelanotide)
Available Strengths	10mg
Physical Appearance	White Lyophilized Powder
Purity	≥ 99% (HPLC/MS Verified)
Molecular Formula	$C_{78}H_{111}N_{21}O_{19}$
Molecular Weight	1646.85 g/mol
CAS Number	75921-69-6
Verification Method	3rd-Party Lab Tested with COA
Storage Instructions	Store at -20°C (Long-term); 2-8°C after reconstitution

Melanotan I (MT-1) Key Features & Benefits

• Selective MC1R Agonist: Optimized for research into natural pigmentation pathways and melanin synthesis.

• Photoprotection Research Subject: Ideal for studies focusing on cellular resilience against UV radiation and DNA protection.

• Pharmaceutical Grade Synthesis: Produced at 99%+ purity to ensure minimal cross-reactivity and high-fidelity experimental data.

• Sterile Freeze-Dried Stability: Vacuum-sealed to resist environmental degradation and maintain peptide potency during transit.

• Independently Verified Purity: Every batch is confirmed via HPLC and Mass Spectrometry for absolute chemical precision.

Melanotan I (MT-1) Research FAQ

How does Melanotan I (MT-1) differ from Melanotan II (MT-2)?

In a laboratory setting, MT-1 is a linear peptide that is highly selective for the MC1R receptor, primarily influencing pigmentation. MT-2 is a cyclic analog that is non-selective, often impacting MC3R and MC4R receptors, which can influence appetite and other physiological systems not related to skin coloration.

What is the advantage of using a 10mg lyophilized vial for research?

The 10mg vial is the standard for precision dosing in metabolic and cosmetic research. Lyophilization ensures the peptide remains stable at room temperature during shipping and prevents the hydrolysis that can occur in liquid-stable products.

How should MT-1 be handled during reconstitution?

Researchers should use bacteriostatic water or sterile saline. To maintain the structural integrity of the 13-amino acid chain, the liquid should be added slowly down the side of the vial, followed by gentle swirling. Harsh agitation or shaking should be avoided to prevent peptide denaturing.

Can Melanotan I be studied for its effects on skin cancer prevention?

MT-1 is frequently used in research models to study how increased melanin serves as a natural defense mechanism. While it is a subject of intense study regarding UV-induced damage, all applications are strictly for laboratory research and not for clinical prevention.

Why Buy Melanotan I online from 99Purity-Peptide?

• Elite Biotech Specialization: We understand that credible data requires pure materials. Our MT-1 is synthesized to meet the highest analytical standards, providing a 99%+ pure medium for your laboratory.

• Discreet & Tracked Logistics: Your research privacy is our priority. All orders are sent in neutral, secure packaging with tracked delivery to ensure safety throughout the USA, UK, and Europe.

• Reliable Batch Consistency: Our manufacturing protocols ensure that the chemical profile of our Melanotan I remains identical batch-after-batch, supporting reproducible data.

• Total Researcher Protection: From 3rd-party lab verification (COA) to secure payment options, we provide the professional reliability that serious biotechnology researchers demand.

Payment Support & Logistics

• Secure Payment Options: We support multiple secure gateways, including Credit Cards, Cryptocurrency (USDT, USDC), PayPal, and Bank Transfers.

• Global Shipping: Fast, tracked delivery available to the United States, United Kingdom, and Europe.

• Processing Time: All orders are professionally handled and dispatched within 1-2 business days after payment confirmation.

Regulatory Disclaimer

99Purity-Peptide is a chemical supplier. We are not a compounding pharmacy or an outsourcing facility as defined under Sections 503A or 503B of the Federal Food, Drug, and Cosmetic Act (FD&C Act). All products are strictly for research, laboratory, or analytical use only and are NOT for human consumption.

References & Academic Links

• Hadley, M. E., & Dorr, R. T. (2006). “Melanocortin peptide therapeutics: historical milestones, clinical studies and commercialization.” Peptides.

• Biolcati, G., et al. (2015). “Afamelanotide for Erythropoietic Protoporphyria.” The New England Journal of Medicine.

• Dorr, R. T., et al. (1996). “Increased melanin content and reduced cell proliferation in human melanocytes exposed to a synthetic $\alpha$-MSH analog.” European Journal of Cancer.

• Luger, T. A., et al. (2003). “The melanocortin system at the interface between inflammation and immune response.” Annals of the New York Academy of Sciences.